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Vertex Pharmaceuticals Incorporated VRTX

Healthcare · Biotechnology · United States · S&P 500

76
Profitability
93
Growth
63
Valuation
27
Financial strength
100
Momentum
97

Based on the available data, Vertex Pharmaceuticals Incorporated gets an algorithmic score of 76/100. It trades at 526.73 $, with a bullish technical trend (RSI 53.5) and 28.7% annual volatility.

Updated: 2026-09-30

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Strengths

  • High ROE (23.5%): generates strong profit on equity.
  • High net margin (35.0%): pricing power / competitive advantage.
  • Sustained revenue growth (10.4% compound annual).
  • Low-debt balance sheet.
  • Low beta (0.30): defensive profile.

Weaknesses

  • —

Fundamentals

P/E30.62
Forward P/E26.21
PEG1.90
P/B6.59
EV/EBITDA25.02
P/S10.60
ROE %23.54
ROA %11.93
Gross margin %54.96
Operating margin %38.05
Net margin %35.00
Revenue growth % (y/y)12.50
Earnings growth % (y/y)8.00
Revenue CAGR %10.35
Earnings CAGR %5.97
Debt/Equity %9.77
Current ratio3.19
FCF yield %2.39
Dividend yield %0.00
Payout %0.00

Returns

1 month-2.8 %
3 months+6.0 %
6 months+18.9 %
YTD+16.5 %
1 year+36.5 %
3 years+50.7 %
5 years+183.5 %

Risk

1-year volatility28.7 %
Beta0.30
5-year max drawdown-29.1 %
Sharpe 1A1.09

Macroeconomic context

Defensive with structural growth (ageing population). Risks: drug-pricing regulation, patents and clinical trials. Low correlation with the cycle. As a US company, its valuation depends on the Fed, 10-year Treasury yields and the US earnings cycle.

How the score is calculated

The score combines profitability (ROE, ROA, net margin), growth (revenue and earnings), valuation (P/E, EV/EBITDA, free cash flow), financial strength (debt and liquidity; not applied to banks and insurers) and momentum (6 and 12-month returns and trend). It is an educational quantitative filter, not a buy or sell recommendation.

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